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Klotho (KL) – G395A Genetic Variant

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Klotho (KL) G395A genetic testing analyzes the rs1207568 variant in the Klotho gene, which is involved in aging-related biological processes, kidney function, and mineral metabolism. The test provides insights into a genetic factor studied in connection with healthy aging, cardiovascular health, and longevity. Its clinical significance is still under investigation.

Detailed information

Product detailed description

Klotho (KL) G395A genetic testing helps identify genetic differences associated with aging-related biological processes, cellular protection, and mineral metabolism. The Klotho gene is often referred to as the "longevity gene" because of its role in regulating biological mechanisms involved in healthy aging.

This genetic test analyzes the G395A (rs1207568) variant in the KL gene, located in the gene's regulatory region, which may influence its expression. The Klotho protein plays an important role in calcium and phosphate metabolism, kidney function, and other physiological processes associated with aging.

Scientific research has investigated potential associations between this genetic variant and cardiovascular health, metabolic function, and age-related changes in the body.

Who may benefit from Klotho genetic testing?

  • Individuals interested in the genetics of healthy aging and longevity.

  • Those seeking to better understand genetic factors related to metabolism and cellular function.

  • People interested in genetic research concerning cardiovascular and kidney health.

  • Individuals looking for additional information about genetic variants studied in preventive health and aging research.

What can the test reveal?

The Klotho G395A genetic test identifies your genotype at this specific location in the KL gene and provides information about a genetic factor investigated in relation to aging and certain chronic conditions.

Important: Carrying a particular genetic variant does not determine lifespan or reliably predict the development of disease. The clinical significance of the G395A variant is still being investigated. This test is primarily informational and does not replace standard medical diagnostics.

Additional parameters

Category: Longevity
Sample Type: Stěr ústní sliznice

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