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This blood test detects antibodies against Proteinase 3 (PR3), an enzyme found in neutrophils. Antibodies against PR3 (cANCA) are often associated with granulomatosis with polyangiitis (GPA), an autoimmune disease affecting blood vessels. The test aids in diagnosing autoimmune vasculitis and helps monitor disease progression and treatment effectiveness. Results should always be discussed with a doctor.
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